Thyroid Lymphoma in Hashimoto’s Thyroiditis CHT

Dr.Guttler’s Comments;
Overview of DLBCL diffuse large B-cell lymphoma and MALT Lymphoma (mucosa-associated lymphoid tissue lymphoma ).
All other types are rare in the thyroid.
Lymphoma Prevalence
DLBCL,  > 50%    MALT (10–23%)
Clinical Behavior.
 DLBCL More aggressive.                   MALT  Less aggressive.
DLBCL Cytology  Large, monotonous lymphoid cells, lymphoepitheliallesions, decreased or absent colloid.
MALT  Cytology   Intermediate-sized cells, lymphoepithelial lesions, reactive lymphoid follicles,plasma cell component.
Radiation and chemotherapy.
Localized, radiation 5-y disease-specificsurvival rates (96–100%).
Disseminated, radiation chemotherapy 5-y disease-specificsurvival rates ( 71–75%).
Thyroid Lymphoma Staging
I E no spread outside the thyroid gland.
II E Local lymph nodes
III E Lymph node on both sides of the diaphram.
VI E Diffuse disease

This is a rare cancer occurring in CHT.

Papillary thyroid cancer is common and the main cancer occurring in CHT.

Thyroid Lymphoma is very rare, but when it happens it is usually in a patient with long standing stable CHT with an enlarged thyroid goiter. This changes one day when the patient notices the thyroid gland is enlarging over a short period of time.

Patients with CHT have a 70-89 times higher chance of getting a thyroid lymphoma compared to normal patients without CHT.

It takes 20-30 years after the onset of CHT to develop thyroid lymphoma.

A thyroid consultation can determine if you have a thyroid lymphoma by neck exam,ultrasound biopsy and flow cytometry.

Call me at 310-393-8860 or email to

Ask for Alicia.


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