Thyroid nodules are a very common occurrence in the general population. In most cases, thyroid nodules are benign, however, even if benign, they can grow and determine compressive symptoms or cosmetic concerns, thus requiring a treatment. Surgical removal of half or the whole thyroid gland represents the standard treatment for symptomatic benign thyroid nodules [1,2,3].s.
Its disadvantages include primarily the lower efficacy in thyroid function normalization as compared to RAI , as well as a very low risk of adverse events (voice change). As a rule of thumb, MITT should be used as a treatment for AFTN only in selected cases, preferably in small AFTN when RAI is contraindicated (pregnant and breastfeeding women) or refused by patient, or in women with an immediate desire to conceive.