Dr.Guttler’s Thyroid Patient Blog Post: Concurrent Use of Thyroid Hormone Therapy and Interfering Medications in Older US Veterans.
1. Thyroid hormone management in older adults is complicated by comorbidities and polypharmacy.
2.The prevalence of concurrent use of thyroid hormone and medications that can interfere with thyroid hormone metabolism (amiodarone, prednisone, prednisolone, carbamazepine, phenytoin, phenobarbital, tamoxifen), and patient characteristics associated with this practice.
The Journal of Clinical Endocrinology & Metabolism, Volume 107, Issue 7, July 2022, Page e2738.
4. 137/538 adults were >65.
5. 168 / 878 (31.4%) patients were on at least 1 interfering medication while on thyroid hormone during the study period.
6. Presence of comorbidities were more likely to be associated with concurrent use of thyroid hormone and interfering medications.
7.Older age (eg, ≥ 85 years; compared with age 65-74 years) was less likely to be associated with this practice.
8.Almost one-third of older adults on thyroid hormone were on medications known to interfere with thyroid hormone metabolism.
9.The complexity of thyroid hormone management in older adults needs to be evaluated by the endocrinologists to look for those drugs that cause problems when taken with T4.
10. Call me at 310-393-8860 or email to thyroid.manager@thyroid.com.
DR.G.
the complexity of thyroid hormone management in older adults, especially in women and minorities.
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